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CIP Chemical Cleaning Technical Guidelines for Reverse Osmosis Systems

The main reason for chemical cleaning (chemical cleaning or IP, i.e., in-place cleaning) of reverse osmosis membrane systems is to restore the performance of the membrane, prolong the service life of the membrane, and ensure the efficient and stable operation of the system.Conventional physical cleaning (e.g., low-pressure washing, air scrubbing) can only remove loose contaminants from the membrane surface, while chemical cleaning can more thoroughly remove stubborn contaminants (e.g., scaling, biofilm, etc.) through the dissolution, dispersion, oxidation or sterilization of chemical reagents

Table of Contents

I. Cleaning Trigger Criteria

II. Pre-Cleaning Preparation

1. System Inspection

2. Safety Precautions

3. Chemical Formulation

Cleaning Phase Chemical Formula Concentration Temperature
Alkaline Cleaning NaOH + EDTA-4Na + Surfactant 0.1%-0.5% 35-40℃
Acid Cleaning Citric Acid/HCl + Corrosion Inhibitor 1%-2% 25-30℃
Disinfection Peracetic Acid/Sodium Bisulfite 0.5%-1% Ambient

4. System Isolation

III. Step-by-Step Cleaning Procedure

Step 1: Low-Pressure Flushing

Step 2: Alkaline Cleaning (Organic/Biofilm Removal)

  1. Circulation:
  2. Soaking:
  3. Drainage:

Step 3: Acid Cleaning (Inorganic Scale Removal)

  1. Circulation:
  2. Endpoint:

Step 4: Disinfection

Step 5: Final Flushing

IV. Post-Cleaning Evaluation

V. Targeted Solutions for Specific Fouling

Fouling Type Symptoms Recommended Solution
Organic Fouling Rapid ΔP rise, stable conductivity Alkaline cleaner (pH11-12) + 50℃ heating
Inorganic Scaling Sudden flow drop, salt rejection decline 2% citric acid + NH3 (pH4) + 40℃ circulation
Biofouling Odor, slimy deposits Alternate 1% peracetic acid and 0.1% NaOH
Colloidal Fouling SDI >5, gradual ΔP rise 0.025% SDBS + EDTA composite cleaning

VI. Safety Protocols

Expected Outcomes:

Note: Use rotary nozzle systems (e.g., GE TurboClean™) to enhance shear force by 3× and cleaning efficiency by 40%+

Hi, I am the author of this article and I have been working in this field for more than 8 years. If you want to know about water treatment related knowledge and products, please feel free to ask me any questions.


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